由 G Tau 著作 · 1999 · 被引用 335 次 — Overview. Interferon‐gamma (IFN‐γ) is a cytokine that plays an important role in inducing and modulating an array of immune responses.
Through cell signaling, interferon gamma plays a role in regulating the immune response of its target cell. A key signaling pathway that is activated by type II ...
Interferon gamma function. Interferon gamma is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor ...
由 F Castro 著作 · 2018 · 被引用 1086 次 — Specifically, IFN-γ plays a major role in activating anticancer immunity, by promoting the activity of CD4 T helper type 1 cells, CD8 cytotoxic T lymphocyte ( ...
由 TN Ellis 著作 · 2004 · 被引用 368 次 — The primary way in which IFN-γ acts as an immunomodulator is through regulation of gene expression. The signal transduction pathways leading from binding of IFN ...
由 K Schroder 著作 · 2004 · 被引用 5523 次 — IFN-γ is a remarkable cytokine that orchestrates many distinct cellular programs through transcriptional control over large numbers of genes.
由 H Ding 著作 · 2022 · 被引用 30 次 — The interferon-gamma (IFN-γ) signaling is critical for both innate and adaptive immunity through binding and activating the IFN-γ receptor (IFNγR), a tetramer ...
由 D Jorgovanovic 著作 · 2020 · 被引用 680 次 — Interferon-γ (IFN-γ) plays a key role in activation of cellular immunity and subsequently, stimulation of antitumor immune-response.
